The following list provides an overview of clinical registries that are currently or were formerly run by the Institute of Biostatistics and Analyses Ltd. An overview of current clinical registries is also available.Directory of registries
VINCI - Virtual patient in cardiology and diabetology
Register of patients with alpha-1-antitrypsin deficiency
The AATD registry study represents a non-interventional multicenter retrospective prospective longitudinal follow-up patients with alpha-1-antitrypsin deficiency.
Educational website focusing on an interactive education of emergency medicine.
Terminated clinical registry of patients with chronic myeloid leukaemia (CML) for the Arab Leukaemia Network.
Terminated clinical registry of patients suffering from age-related macular degeneration (AMD) or diabetic macular oedema (DMO) who were treated with anti-VEGF medications.
Terminated survey of patient compliance and the administration of antiplatelet therapy in patients with acute coronary syndrome who have been hospitalised in PCI centres all over the Czech Republic.
Multicentric system for the assessment of the progress and results of biological therapy of ankylosing spondylitis, juvenile idiopathic arthritis, psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus.
Evaluation of efficacy of new spectroscopic biomarkers for the detection of early-stage pancreatic cancer.
The BRESCA registry will obtain retrospective and prospective data of patients diagnosed with advanced breast cancer treated with targeted therapy. This clinical data source will reflect the real clinical practice of oncological therapy in the Czech Republic.
International clinical registry of patients with chronic myeloid leukaemia.
International clinical registry of patients with chronic myeloid leukaemia.
Terminated clinical registry of patients suffering from severe persisting allergic asthma who were treated with omalizumab (Xolair®).
The aim of the project is to collect and evaluate data from real clinical practice, which are related to the administration of CAR-T cell therapy in patients with certain hematological malignancies who face poor prognosis. CAR-T cell therapy is currently indicated in adult patients with certain types of non-Hodgkin's lymphoma, incl. aggressive, relapsing or refractory diffuse large B-cell lymphoma, primary mediastinal B-lymphoma, high-grade B-lymphoma, transformed follicular lymphoma and mantle cell lymphoma; and in pediatric patients and patients under 25 years of age with acute lymphoblastic leukemia (B-ALL) who do not respond to a defined number of standard therapy lines.
System of informational support for the Cervical Cancer Screening Programme in the Czech Republic.
The CESAR project is a national, multicenter, retrospective-prospective, observational, non-interventional study of patients with severe asthma. Data collection will take place in designated centers for the treatment of severe asthma.
Clinical registry of neuromodulation techniques applied in patients suffering from chronic pain.
Non-interventional multicentre observational prospective database focusing on the collection and analysis of data on real mortality and morbidity in an unselected population of COPD patients.
The CORECT registry is a non-interventional post-registration database focused on collection of epidemiological and clinical data of patients with colorectal carcinoma (CRC) treated with bevacizumab, cetuximab, and panitumumab. The project was initiated in July 2011 by the Czech Society for Oncology. Obtained data allow for monitoring of CRC patients' treatment and its results. Institute of Biostatistics and Analyses Ltd, a spin-off company of the Masaryk University, provides management and other services to this project.
Non-interventional multicentre retrospective and prospective longitudinal monitoring of patients with inflammatory bowel disease (IBD) who have been treated with biological therapies.
Clinical registry monitoring cases of bladder cancers treated with cystectomy and consecutive treatment.
Terminated clinical registry of patients with acute coronary syndromes in the Czech Republic.
Terminated cross-sectional registry of patients with acute coronary syndromes in the Czech Republic.
The Czech National Haemophilia Programme (CNHP) is a non-interventional multicentre prospective study which monitors inherited haemorrhagic disorders: haemophilia, von Willebrand's disease and other haemorrhagic disorders.
The D-side project is a research initiative of the Plastic Surgery Clinic at St. Anny and collaborates on the project with the Institute of Biostatistics and Analysis, s.r.o. Specifically, it involves the collection of clinical data of patients regarding their decision (not) to undergo preventive removal of the mammary gland.
Non-interventional, multicentre, retrospective and prospective study of patients with brain tumours, who have been treated in the Czech Republic according to the common clinical practice.
Detailed assessment of safety and efficacy of hybrid ablation of persistent and long-standing persistent atrial fibrillation using a combined (hybrid) approach – surgical thoracoscopic epicardial ablation and a subsequent complex cardiological endocardial ablation.
Multicentre research database for implementation of parametric monitoring of severe sepsis treatment directly in clinical practice.
Terminated multicentre, national, observational, non-interventional, prospective study of paediatric patients with an acute infection of respiratory tract who were treated with erdosteine (Erdomed®).
Clinical registry of haemato-oncological patients in which antimycotic therapy has been administered.
Multicentre, non-interventional, retrospective and prospective monitoring of patients with chronic HCV infection who have been treated with direct-acting antiviral agents (DAAs) or with standard therapy.
The HCC-VP.COM project presents a series of case studies of virtual patients with hepatocellular carcinoma. The interactive educational content was created for the purpose of the lifelong learning of physicians, above all in the field of oncology, and aims to develop competencies in clinical reasoning. This international project expands the range of on-line learning activities, especially for young doctors, to include gamification elements in the lifelong learning process.
Terminated international project covering the Central European region and focusing on the collection and analysis of data on haemophiliac patients, including health care quality assessment.
Terminated registry of patients with hereditary gynaecological cancers, including breast cancer.
A central registry dealing with the implantation of implantable cardioverter-defibrillators (ICD).
Registry of EGFR mutation testing results in patients with non-small-cell lung cancer (NSCLC) in the Czech Republic.
System of informational support for the Colorectal Cancer Screening Programme in the Czech Republic.
Virtual patients, serious and serious games represent learning objects that are increasingly used in the lifelong education of doctors and other health professionals. The Leukemik.cz project presents a series of virtual patients - interactive case studies that allow you to go through diagnostic and therapeutic procedures for chronic myeloid leukemia (CML) and acute lymphoblastic leukemia with a positive Philadelphia chromosome (Ph+ ALL). Although the greatest application is expected mainly among hemato-oncologists, this educational IT platform can become an interesting source of information for specialists in other medical fields as well.
Terminated registry of morphologically examined breast cancers, with particular emphasis on the collection of data regarding the examination of HER2/neu status in the Czech population.
System of informational support for the Breast Cancer Screening Programme in the Czech Republic.
The MELANOM registry is a time-limited non-interventional post-authorization data collection on patients with melanoma. The project aims to monitor patients with modern expensive treatment of advanced disease and also monitoring of patients with adjuvant treatment. Data collection started in December 2020. The duration of the study is planned for 5 years (until the end of 2025).
Registry collecting data on patients with myasthenia gravis, a rare autoimmune neuromuscular disorder
Multicentric non-interventional prospective study assessing antiemetic guidelines consistency in chemotherapy-induced nausea and vomiting (CINV) prophylaxis and the impact of CINV on the quality of life on cancer patients receiving moderately emetogenic chemotherapy (MEC) or highly emetogenic chemotherapy (HEC).
Terminated international clinical registry gathering data on the management of patients with non-small cell lung cancer (NSCLC) who had been diagnosed at the clinical stage III.
Prospective observational multinational multicentre study aiming to cover all health care facilities providing anaesthesia in the peripartal period in the Czech Republic and Slovakia, thus getting the most accurate image possible about this segment of anaesthesiology.
Terminated parametric collection of basic clinical data on paediatric cancer patients, interactive analytical reports.
Clinical registry of pleural mesothelioma patients who have been treated with pemetrexed (Alimta®).
Terminated project developing a data background for the monitoring of numbers and indications of PET/CT scans in the clinical practice of Czech health care facilities.
Non-interventional, multicentre, prospective study monitoring the development and treatment of congenital dysfunctions of the immune system.
Terminated clinical registry of patients with chronic obstructive pulmonary disease (COPD) in Central and Eastern Europe.
Randomised trial comparing the effectiveness of ticagrelor and prasugrel in patients with ST segment elevation myocardial infarction (STEMI) who have been treated with primary PCI.
Terminated registry of PAH (pulmonary arterial hypertension) patients who were treated with parenteral prostanoids.
The RCC-VP.COM project presents a series of case studies of virtual patients with renal cell carcinoma. The interactive educational content was created for the purpose of lifelong learning of physicians, especially in the fields of oncology and urology, and aims to develop competencies in clinical reasoning.
REaDY (REgistry of muscular DYstrophies) is a clinical registry of patients suffering from Duchenne/Becker's muscular dystrophy (DMD/BMD), spinal muscular atrophy (SMA), myotonic dystrophy (DM) or facioscapulohumeral muscular dystrophy (FSHD).
Terminated registry of paediatric and adult patients with home-administered parenteral nutrition.
Terminated clinical registry that monitored the epidemiology of gastrointestinal stromal tumours (GIST) as well as therapeutic approaches and treatment results in GIST patients in the Czech Republic and Slovakia.
The portal rektum.cz is dedicated mainly to the education of health care professionals on the issue of rectal cancer, which is diagnosed as C20 under the ICD-10 classification.
The RENIS II project is intended to cover the monitoring of patients with renal cell carcinoma (RCC).
Clinical registry focused on non-interventional monitoring of patients with pulmonary hypertension.
International clinical registry of patients with monoclonal gammopathies.
Terminated clinical registry of patients who underwent autologous stem cell transplantation and who were treated with plerixafor.
Registry of patients with first acute ischaemic stroke of the carotid circulation with permanent neurological deficit.
Clinical registry collecting data on patients who have undergone transcatheter aortic valve implantation (TAVI).
Registry of patients with essential thrombocythaemia or thrombocythaemia associated with another myeloproliferative disorder who have been treated with anagrelide (Thromboreductin®).
Clinical registry of non-small cell lung cancer (NSCLC) patients who have been treated with bevacizumab (Avastin®), erlotinib (Tarceva®), gefitinib (Iressa®), pemetrexed (Alimta®), afatinib (Giotrif®) and/or nintedanib (Vargatef®).